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Familial atypical multiple mole and melanoma (FAMMM) syndrome

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Familial atypical multiple mole and melanoma (FAMMM) syndrome is an inherited tendency to develop melanoma.

FAMMM syndrome is present when:

  • Melanoma has been diagnosed in a family member, including grandparents, aunts, uncles, and cousins.
  • Several family members have large numbers of moles (often more than 50), some of which may be abnormal, or atypical, moles.

Some people with FAMMM syndrome have certain gene changes that also increase their risk for other cancers, such as pancreatic cancer.

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